Associate Principal Scientist, Gene Editing and Biologics Research

Location: Bridgewater
Posted on: June 23, 2025

Job Description:

Company Description Insmed is a global biopharmaceutical company on a mission to transform the lives of patients living with serious and rare diseases. Our most valuable resource is our employees, and everything we do is motivated by a patients-first mentality. We are dedicated to growing our team with talented individuals from around the world who are willing to challenge the status quo, solve problems, and work collaboratively with a sense of urgency and compassion. Guided by our core values of collaboration, accountability, passion, respect, and integrity, we aim to foster an inclusive, diverse, and flexible work environment, where our employees are recognized for leaning in and rolling up their sleeves. If you share our vision and want to work with the most dedicated people in the biopharma industry, come to Insmed to accelerate your career. Recognitions Consistently Ranked Science 's Top Employer Insmed is dedicated to creating a collaborative environment where our team can thrive. Every day, our employees turn their passion for science and research into innovative solutions for patients. That's why we've been named the No. 1 company to work for in the biopharma industry in Science 's Top Employers survey for four years in a row. A Certified Great Place to Work® We believe our company is truly special, and our employees agree. In July 2024, we became Great Place to Work-certified in the U.S. for the fourth year in a row. We are also honored to have been listed on the Best Workplaces in Biopharma™, Best Workplaces in New York™, PEOPLE® Companies That Care, Best Workplaces for Women™, Best Workplaces for Millennials™, and Best Medium Workplaces™ lists. Overview We are seeking a highly motivated, creative, and passionate Associate Principal Scientist to lead discovery and development campaigns focused on next-generation biotherapies and gene editing technologies. The candidate will work within a multidisciplinary team focused on the design, engineering, characterization, formulation development, and translational pharmacology models of ground-breaking biotherapeutics. Responsibilities Responsibilities Drive biomolecular engineering and pharmacology efforts within Insmed research projects, including strategy and methods development Handle, mentor, and develop a team of project scientists focused on protein engineering and next-generation gene editing technologies Conceptualize, construct, validate, and implement high throughput screening platforms to enable candidate selection from large panels and/or combinatorial libraries of engineered protein variants Develop, validate, and deploy functional and pharmacological assays to characterize protein performance in vitro and in vivo Establish and handle partnerships with research teams from computational biology, immunology, bioanalytical, in vivo, and formulation science Establish and handle partnerships with cross functional team members from DMPK, toxicology, translational bioanalytics, technical operations, and program management Maintain accurate, detailed, and timely records of methods development, experimental data, and data analysis in an electronic notebook system and technical reports Perform data review to ensure accuracy, completeness, and validity Present scientific results to the larger Insmed research group and external scientific community, as needed Assist with coordination and day-to-day management of site operations Qualifications Requires a minimum of a PhD and 9 years of experience in molecular and cellular biology, bioengineering, biochemistry, immunology, microbiology, or related field Must have demonstrated management and leadership experience Deep expertise in therapeutic gene editing required Requires mastery of applied molecular and cellular biology, protein biochemistry, recombinant DNA technology, protein mutagenesis, and high throughput library screening Experience with translational in vivo models of genetic disease and therapeutic gene therapy/editing required Excellent communication (verbal and written) and problem-solving skills required Highly organized with attention to detail, clarity, accuracy, and conciseness Salary Range $135,000 - $189,667 a year Compensation & Benefits At Insmed, we're committed to investing in every team member's total well-being, now and in the future. Our benefit programs vary by country but we offer the following to all Insmed team members, regardless of geographic location: Flexible approach to how we work Health benefits and time-off plans Competitive compensation package, including bonus Equity Awards (Long-Term Incentives) Employee Stock Purchase Plan (ESPP) For more information on U.S. benefits click here . Additional Information Insmed Incorporated is an Equal Opportunity employer. We do not discriminate in hiring on the basis of physical or mental disability, protected veteran status, or any other characteristic protected by federal, state, or local law. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law. Unsolicited resumes from agencies should not be forwarded to Insmed. Insmed will not be responsible for any fees arising from the use of resumes through this source. Insmed will only pay a fee to agencies if a formal agreement between Insmed and the agency has been established. The Human Resources department is responsible for all recruitment activities; please contact us directly to be considered for a formal agreement. Insmed is committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, its services, programs, and activities. To request reasonable accommodation to participate in the job application or interview process, please contact us by email at TotalRewards@insmed.com and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address. Applications are accepted for 5 calendar days from the date posted or until the position is filled.

Keywords: , East Brunswick , Associate Principal Scientist, Gene Editing and Biologics Research, Science, Research & Development , Bridgewater, New Jersey